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BACE1 antibody (N-Term)

The Rabbit Polyclonal anti-BACE1 antibody has been validated for WB and ELISA. It is suitable to detect BACE1 in samples from Mouse.
Catalog No. ABIN6735182

Quick Overview for BACE1 antibody (N-Term) (ABIN6735182)

Target

See all BACE1 Antibodies
BACE1 (Beta-secretase 1 (BACE1))

Reactivity

  • 95
  • 55
  • 46
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
Mouse

Host

  • 81
  • 21
  • 1
  • 1
Rabbit

Clonality

  • 75
  • 29
Polyclonal

Conjugate

  • 73
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BACE1 antibody is un-conjugated

Application

  • 81
  • 45
  • 36
  • 28
  • 22
  • 18
  • 13
  • 13
  • 12
  • 10
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Binding Specificity

    • 16
    • 13
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Specificity

    The mouse sequence has high degree of homology (100 % ) with human and 90 % with rat BACE/Asp2. No significant sequence homology exists with BACE2/Aps1, a homolog of BACE, or other Asps. Antibody cross-reactivity in various species is not established.

    Purification

    Immunoaffinity purified

    Immunogen

    A 10 aa peptide near the NT of mouse BACE/Asp2 (1) conjugated to KLH.

    Isotype

    IgG
  • Application Notes

    Approved: ELISA (1:10000 - 1:100000), WB (1 - 10 μg/mL)

    Usage: Suitable for use in ELISA and Western Blot. ELISA: 1:10000-1:100000 using 50-100 ng of control peptide per well. Western Blot: 1-10 μg/mL using ECL.

    Comment

    Target Species of Antibody: Mouse

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS,  pH 7.4, 0.1 % BSA, 40 % glycerol.

    Handling Advice

    Avoid repeat freeze-thaw cycles.

    Storage

    4 °C,-20 °C

    Storage Comment

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target

    BACE1 (Beta-secretase 1 (BACE1))

    Alternative Name

    BACE1 / BACE

    Background

    Name/Gene ID: BACE1
    Subfamily: Aspartic A1
    Family: Protease

    Synonyms: BACE1, APP beta-secretase, Asp 2, ASP2, Aspartyl protease 2, Aspartylprotease 2, Beta-secretase, Beta-site APP-cleaving enzyme, BACE, HSPC104, KIAA1149, B-Secretase, Beta-secretase 1, Memapsin-2

    Gene ID

    23621

    UniProt

    P56817
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