Adenosine A2a Receptor antibody (N-Term)
Quick Overview for Adenosine A2a Receptor antibody (N-Term) (ABIN6735510)
Target
See all Adenosine A2a Receptor (ADORA2A) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Specificity
- Recognizes Adenosine A2a Receptor. Species cross-reactivity: Human, bovine and porcine A2a receptors. The canine A2aR21 has homology of 43 % (13/30 AA) with rat, 80 % (24/30 AA) with human and 70 % (21/30 AA) with G. pig A2aR sequences.
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Purification
- Protein A purified
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Immunogen
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A 30 amino acid sequence as corresponding to canine A2aR gene (1). This region is within the 4th C-terminal intracellular domain. A cysteine has been added at the NH2 terminus for coupling to KLH.
Type of Immunogen: Synthetic peptide -
Isotype
- IgG
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Application Notes
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Approved: ELISA (1:10000 - 1:50000), WB (1 - 10 μg/mL)
Usage: Suitable for use in ELISA and Western Blot. Western Blot: 1-10 μg/mL using ECL. ELISA: 1:10000-1:50000 using 50-100 ng A1R control peptide/well. Positive control: A0869-56E. -
Comment
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Target Species of Antibody: Dog
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Tris, pH 7.5, 0.2 % BSA, 0.05 % sodium azide, 40 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Adenosine A2a Receptor (ADORA2A)
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Alternative Name
- ADORA2A/Adenosine A2A Receptor
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Background
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Name/Gene ID: ADORA2A
Subfamily: Adenosine
Family: GPCR
Synonyms: ADORA2A, Adenosine receptor A2a, ADORA2, A2a receptor, Adenosine A2a receptor, Adenosine A2 receptor, Adenosine receptor subtype A2a, HA2aR, RDC8 -
Gene ID
- 135
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UniProt
- P29274
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Pathways
- Neurotrophin Signaling Pathway, cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour, Cancer Immune Checkpoints
Target
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