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CTNNB1 antibody (pTyr654)
This anti-CTNNB1 antibody is a Mouse Monoclonal antibody detecting CTNNB1 in WB and ELISA. Suitable for Human.
Quick Overview for CTNNB1 antibody (pTyr654) (ABIN6735572)
Target
See all CTNNB1 Antibodies
CTNNB1
(Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
Reactivity
All reactivities for CTNNB1 antibodies
Human
Host
All hosts for CTNNB1 antibodies
Mouse
Clonality
All clonalities for CTNNB1 antibodies
Monoclonal
Conjugate
All conjugates for CTNNB1 antibodies
This CTNNB1 antibody is un-conjugated
Application
All applications for CTNNB1 antibodies
Western Blotting (WB), ELISA
Clone
1B11
Product Details anti-CTNNB1 Antibody
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Binding Specificity
All epitopes for CTNNB1 antibodies
pTyr654
Specificity
Recognizes beta-catenin phosphorylated at Tyr654 and -catenin phosphorylated at Tyr654. Detects bands of ~90kD (beta-catenin) and ~70kD (gamma-catenin). Due to sequence homologies of the phospho-epitope surrounding Tyr654, there may be cross-reactions with other proteins (e. g., Annexin A11 at 56kD, desmoplakin at 81kD, TNF-alpha-induced protein 2 at 73kD, ribosomal protein S6 kinase alpha 6 at 90kD). Species cross-reactivity: human, mouse and canine.
Cross-Reactivity
Dog (Canine), Mouse (Murine)
Purification
Gel Filtration Chromatography
Immunogen
Synthetic peptide corresponding to a portion of beta-catenin phosphorylated at Tyr654. Epitope: phosphotyrosine 654 (VATpYAAA).
Isotype
IgG1
Alternatives
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anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (N-Term) antibody
KO Validated
CTNNB1
Reactivity: Human
WB, IHC, IF, FACS, IHC (p), IP, ICC, IHC (fro), ChIP, CUT&RUN, IHC (wm)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
ELISA, WB (1 µg/mL)
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS, 0.1% sodium azide, G, Sucrose, 40% glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Long term: Add glycerol (40-50%) -20°C, Short term: +4°C
Target Details for CTNNB1
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Target
CTNNB1
(Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
Alternative Name
CTNNB1 / Beta Catenin
Background
Standard Gene Symbol: CTNNB1, Gene Family: Catenin, Synonyms: CTNNB1, Beta-catenin, Catenin beta-1, CTNNB, Beta Catenin
Gene ID
1499
UniProt
P35222
Pathways
WNT Signaling , Intracellular Steroid Hormone Receptor Signaling Pathway , Peptide Hormone Metabolism , Regulation of Muscle Cell Differentiation , Cell-Cell Junction Organization , Tube Formation , Maintenance of Protein Location , Signaling Events mediated by VEGFR1 and VEGFR2
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