CTNNB1 antibody (pTyr654)

Catalog No. ABIN6735572

This anti-CTNNB1 antibody is a Mouse Monoclonal antibody detecting CTNNB1 in WB and ELISA. Suitable for Human.

Quick Overview for CTNNB1 antibody (pTyr654) (ABIN6735572)

Target: CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CTNNB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1B11

Product Details anti-CTNNB1 Antibody

Binding Specificity: pTyr654

Specificity: Recognizes beta-catenin phosphorylated at Tyr654 and -catenin phosphorylated at Tyr654. Detects bands of ~90kD (beta-catenin) and ~70kD (gamma-catenin). Due to sequence homologies of the phospho-epitope surrounding Tyr654, there may be cross-reactions with other proteins (e. g., Annexin A11 at 56kD, desmoplakin at 81kD, TNF-alpha-induced protein 2 at 73kD, ribosomal protein S6 kinase alpha 6 at 90kD). Species cross-reactivity: human, mouse and canine.

Cross-Reactivity: Dog (Canine), Mouse (Murine)

Purification: Gel Filtration Chromatography

Immunogen: Synthetic peptide corresponding to a portion of beta-catenin phosphorylated at Tyr654. Epitope: phosphotyrosine 654 (VATpYAAA).

Isotype: IgG1

Application Details

Application Notes: ELISA, WB (1 µg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1% sodium azide, G, Sucrose, 40% glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Long term: Add glycerol (40-50%) -20°C, Short term: +4°C

Target Details for CTNNB1

Target: CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

Alternative Name: CTNNB1 / Beta Catenin

Background: Standard Gene Symbol: CTNNB1, Gene Family: Catenin, Synonyms: CTNNB1, Beta-catenin, Catenin beta-1, CTNNB, Beta Catenin

Gene ID: 1499

UniProt: P35222

Pathways: WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2