KCNN3 antibody (AA 642-691)

Catalog No. ABIN6736410

Product Details anti-KCNN3 Antibody

Target: KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))

Binding Specificity: AA 642-691

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Rabbit, Bat, Monkey, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human KCNN3

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Rabbit, Pig, Guinea pig (100%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa642-691 of human KCNN3 (Q9UGI6, NP_002240). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Pig, Opossum, Guinea pig (100%), Horse (92%), Zebra finch (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for KCNN3

Target: KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))

Alternative Name: KCNN3 / SK3 (KCNN3 Products)

Background: Name/Gene ID: KCNN3
Subfamily: Potassium channel - calcium-activated
Family: Ion Channel

Synonyms: KCNN3, KCa2.3, HSK3, SKCa 3, SKCA3, K3, SK3

Gene ID: 3782

NCBI Accession: NP_002240

UniProt: Q9UGI6