PTPN2 antibody (AA 201-250)

Catalog No. ABIN6738161

Product Details anti-PTPN2 Antibody

Target: PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))

Binding Specificity: AA 201-250

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Dog, Cow, Zebrafish (Danio rerio), Chicken, Monkey, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Human PTPN2 / TCPTP

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Rabbit, Horse, Guinea pig, Chicken, Xenopus, Zebrafish (100%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa201-250 of human PTPN2 (P17706). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Galago, Marmoset, Mouse, Rat, Dog, Bovine, Rabbit, Horse, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Lizard, Xenopus, Zebrafish (100%), Stickleback, Sea squirt, Drosophila, Beetle (92%), Orangutan, Monkey, Elephant, Bat, Pig, Platypus (85%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P, WB

Usage: ELISA titer using peptide based assay: 1:312500. Western Blot: Suggested dilution at 0.5 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1:50000 - 100000 as second antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled Water.

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for PTPN2

Target: PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))

Alternative Name: PTPN2 / TC-PTP (PTPN2 Products)

Background: Name/Gene ID: PTPN2
Subfamily: NT1
Family: Protein Phosphatase

Synonyms: PTPN2, PTN2, TC-PTP, TCELLPTP, PTPT, Tc45, TC48, TCPTP

Gene ID: 5771

UniProt: P17706

Pathways: EGFR Signaling Pathway, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling