PTPN2 antibody (AA 201-250)

Catalog No. ABIN6738161

The Rabbit Polyclonal anti-PTPN2 antibody has been validated for WB, IHC and IHC (p). It is suitable to detect PTPN2 in samples from Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Dog, Cow, Zebrafish (Danio rerio), Chicken, Monkey and Xenopus laevis.

Quick Overview for PTPN2 antibody (AA 201-250) (ABIN6738161)

Target: PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Dog, Cow, Zebrafish (Danio rerio), Chicken, Monkey, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PTPN2 Antibody

Binding Specificity: AA 201-250

Specificity: Human PTPN2 / TCPTP

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Rabbit, Horse, Guinea pig, Chicken, Xenopus, Zebrafish (100%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa201-250 of human PTPN2 (P17706). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Galago, Marmoset, Mouse, Rat, Dog, Bovine, Rabbit, Horse, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Lizard, Xenopus, Zebrafish (100%), Stickleback, Sea squirt, Drosophila, Beetle (92%), Orangutan, Monkey, Elephant, Bat, Pig, Platypus (85%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P, WB

Usage: ELISA titer using peptide based assay: 1:312500. Western Blot: Suggested dilution at 0.5 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1:50000 - 100000 as second antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled Water.

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for PTPN2

Target: PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))

Alternative Name: PTPN2 / TC-PTP

Background: Name/Gene ID: PTPN2
Subfamily: NT1
Family: Protein Phosphatase

Synonyms: PTPN2, PTN2, TC-PTP, TCELLPTP, PTPT, Tc45, TC48, TCPTP

Gene ID: 5771

UniProt: P17706

Pathways: EGFR Signaling Pathway, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling