PDE1C antibody (AA 431-480)

Catalog No. ABIN6741846

The Rabbit Polyclonal anti-PDE1C antibody has been validated for WB. It is suitable to detect PDE1C in samples from Human, Mouse, Rat, Cow and Bat.

Quick Overview for PDE1C antibody (AA 431-480) (ABIN6741846)

Target: PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))

Reactivity: Human, Mouse, Rat, Cow, Bat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE1C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDE1C Antibody

Binding Specificity: AA 431-480

Specificity: Human PDE1C

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Rat, Bovine (100%) Dog, Rabbit, Horse, Guinea pig (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa431-480 of human PDE1C (Q8TAE4, NP_005011). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Rat, Bovine, Bat (100%), Marmoset, Dog, Rabbit, Horse, Guinea pig (92%), Elephant (84%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. ELISA titer in peptide based assay: 1:1562500.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for PDE1C

Target: PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))

Alternative Name: PDE1C

Background: Name/Gene ID: PDE1C
Subfamily: PDE - cAMP/cGMP dual-specific, Ca/Calmodulin-dependent
Family: Phosphodiesterase

Synonyms: PDE1C, HCam-3, Hcam3, Phosphodiesterase 1c, Cam-PDE 1C

Gene ID: 5137

NCBI Accession: NP_005011

UniProt: Q14123

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma