TMCO4 antibody (AA 355-404)

Catalog No. ABIN6746423

The Rabbit Polyclonal anti-TMCO4 antibody has been validated for WB. It is suitable to detect TMCO4 in samples from Human, Cow, Guinea Pig, Horse, Mouse, Rabbit, Rat, Bat, Chicken and Monkey. There are 5+ publications available.

Quick Overview for TMCO4 antibody (AA 355-404) (ABIN6746423)

Target: TMCO4 (Transmembrane and Coiled-Coil Domains 4 (TMCO4))

Reactivity: Human, Cow, Guinea Pig, Horse, Mouse, Rabbit, Rat, Bat, Chicken, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMCO4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TMCO4 Antibody

Binding Specificity: AA 355-404

Specificity: Human TMCO4

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Rat, Horse, Chicken (100%) Dog (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa355-404 of human TMCO4 (Q5TGY1, NP_859070). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Bovine, Bat, Rabbit, Horse, Guinea pig, Turkey, Zebra finch, Chicken (100%), Dog, Opossum, Platypus (92%), Stickleback (84%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-TMCO4 antibody (ABIN6746423)

Landsend, Amiry-Moghaddam, Matsubara, Bergersen, Usami, Wenthold, Ottersen: "Differential localization of delta glutamate receptors in the rat cerebellum: coexpression with AMPA receptors in parallel fiber-spine synapses and absence from climbing fiber-spine synapses." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 17, Issue 2, pp. 834-42, (1997) (PubMed).

Zuo, De Jager, Takahashi, Jiang, Linden, Heintz: "Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene." in: Nature, Vol. 388, Issue 6644, pp. 769-73, (1997) (PubMed).

Hirano, Kasono, Araki, Mishina: "Suppression of LTD in cultured Purkinje cells deficient in the glutamate receptor delta 2 subunit." in: Neuroreport, Vol. 6, Issue 3, pp. 524-6, (1995) (PubMed).

Kashiwabuchi, Ikeda, Araki, Hirano, Shibuki, Takayama, Inoue, Kutsuwada, Yagi, Kang: "Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice." in: Cell, Vol. 81, Issue 2, pp. 245-52, (1995) (PubMed).

Araki, Meguro, Kushiya, Takayama, Inoue, Mishina: "Selective expression of the glutamate receptor channel delta 2 subunit in cerebellar Purkinje cells." in: Biochemical and biophysical research communications, Vol. 197, Issue 3, pp. 1267-76, (1994) (PubMed).

Target Details for TMCO4

Target: TMCO4 (Transmembrane and Coiled-Coil Domains 4 (TMCO4))

Alternative Name: TMCO4

Background: Name/Gene ID: TMCO4

Synonyms: TMCO4, RP5-1056L3.6

Gene ID: 255104

NCBI Accession: NP_859070

UniProt: Q5TGY1