TMCO4 antibody (AA 355-404)

Catalog No. ABIN6746423

There are 5+ publications for this product available. The Rabbit Polyclonal anti-TMCO4 antibody is suitable to detect TMCO4 in samples from Human, Cow, Guinea Pig, Horse, Mouse, Rabbit, Rat, Bat, Chicken and Monkey. It has been validated for WB.

Quick Overview for TMCO4 antibody (AA 355-404) (ABIN6746423)

Target: TMCO4 (Transmembrane and Coiled-Coil Domains 4 (TMCO4))

Reactivity: Human, Cow, Guinea Pig, Horse, Mouse, Rabbit, Rat, Bat, Chicken, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMCO4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TMCO4 Antibody

Binding Specificity: AA 355-404

Specificity: Human TMCO4

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Rat, Horse, Chicken (100%) Dog (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa355-404 of human TMCO4 (Q5TGY1, NP_859070). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Bovine, Bat, Rabbit, Horse, Guinea pig, Turkey, Zebra finch, Chicken (100%), Dog, Opossum, Platypus (92%), Stickleback (84%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-TMCO4 antibody (ABIN6746423)

Landsend, Amiry-Moghaddam, Matsubara, Bergersen, Usami, Wenthold, Ottersen: "Differential localization of delta glutamate receptors in the rat cerebellum: coexpression with AMPA receptors in parallel fiber-spine synapses and absence from climbing fiber-spine synapses." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 17, Issue 2, pp. 834-42, (1997) (PubMed).

Zuo, De Jager, Takahashi, Jiang, Linden, Heintz: "Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene." in: Nature, Vol. 388, Issue 6644, pp. 769-73, (1997) (PubMed).

Hirano, Kasono, Araki, Mishina: "Suppression of LTD in cultured Purkinje cells deficient in the glutamate receptor delta 2 subunit." in: Neuroreport, Vol. 6, Issue 3, pp. 524-6, (1995) (PubMed).

Kashiwabuchi, Ikeda, Araki, Hirano, Shibuki, Takayama, Inoue, Kutsuwada, Yagi, Kang: "Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice." in: Cell, Vol. 81, Issue 2, pp. 245-52, (1995) (PubMed).

Araki, Meguro, Kushiya, Takayama, Inoue, Mishina: "Selective expression of the glutamate receptor channel delta 2 subunit in cerebellar Purkinje cells." in: Biochemical and biophysical research communications, Vol. 197, Issue 3, pp. 1267-76, (1994) (PubMed).

Target Details for TMCO4

Target: TMCO4 (Transmembrane and Coiled-Coil Domains 4 (TMCO4))

Alternative Name: TMCO4

Background: Name/Gene ID: TMCO4

Synonyms: TMCO4, RP5-1056L3.6

Gene ID: 255104

NCBI Accession: NP_859070

UniProt: Q5TGY1