DMPK antibody (AA 323-372)

Catalog No. ABIN6747077

The Rabbit Polyclonal anti-DMPK antibody has been validated for WB, IHC and IHC (p). It is suitable to detect DMPK in samples from Human, Mouse, Cow, Dog, Guinea Pig and Bat.

Quick Overview for DMPK antibody (AA 323-372) (ABIN6747077)

Target: DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Bat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMPK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DMPK Antibody

Binding Specificity: AA 323-372

Brand: IHC-plus™

Specificity: Human DMPK

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Dog, Bovine, Guinea pig (100%) Horse (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa323-372 of human DMPK (Q09013, NP_004400). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Mouse, Elephant, Panda, Dog, Bovine, Bat, Guinea pig (100%), Monkey, Marmoset, Horse (92%), Galago (84%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. ELISA titer in peptide based assay: 1:312500.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with 50 μL sterile ddH2O.

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for DMPK

Target: DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))

Alternative Name: DMPK / DM

Background: Name/Gene ID: DMPK
Subfamily: DMPK
Family: Protein Kinase

Synonyms: DMPK, DM-kinase, DM1, DM1PK, DM protein kinase, DM1 protein kinase, DMK, MDPK, Myotonic dystrophy kinase, MT-PK, Myotonin kinase, MtPK, Myotonic protein kinase, Myotonin protein kinase A, Thymopoietin homolog, DM, Myotonin-protein kinase

Gene ID: 1760

NCBI Accession: NP_004400

UniProt: Q09013

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development