S1PR1 antibody (AA 226-275)

Catalog No. ABIN6749170

This Rabbit Polyclonal antibody specifically detects S1PR1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Pig, Rabbit, Horse and Hamster.

Quick Overview for S1PR1 antibody (AA 226-275) (ABIN6749170)

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Rabbit, Horse, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S1PR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-S1PR1 Antibody

Binding Specificity: AA 226-275

Specificity: Human S1PR1 / EDG1

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Rabbit, Horse (100%) Guinea pig (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa226-275 of human S1PR1 (P21453, NP_001391). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Marmoset, Mouse, Rat, Hamster, Dolphin, Panda, Dog, Cat, Bovine, Rabbit, Horse, Pig, Opossum (100%), Monkey, Shrew, Elephant, Bat, Guinea pig, Platypus (92%), Turkey, Zebra finch (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for S1PR1

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Alternative Name: S1PR1 / EDG1 / S1P1

Background: Name/Gene ID: S1PR1
Subfamily: Lysophospholipid/Lysosphingolipid
Family: GPCR

Synonyms: S1PR1, CD363, CD363 antigen, CHEDG1, ECGF1, EDG-1, D1S3362, EDG1, S1P1, S1P receptor Edg-1, S1P receptor 1

Gene ID: 1901

NCBI Accession: NP_001391

UniProt: P21453

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2