ACVR2B antibody (AA 287-336)

Catalog No. ABIN2614264

This anti-ACVR2B antibody is a Rabbit Polyclonal antibody detecting ACVR2B in WB, IHC and IHC (p). Suitable for Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Sheep, Zebrafish (Danio rerio), Pig, Bat, Hamster and Monkey.

Quick Overview for ACVR2B antibody (AA 287-336) (ABIN2614264)

Target: ACVR2B (Activin A Receptor, Type IIB (ACVR2B))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Sheep, Zebrafish (Danio rerio), Pig, Bat, Hamster, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACVR2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ACVR2B Antibody

Binding Specificity: AA 287-336

Brand: IHC-plus™

Specificity: Human ACVR2B

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa287-336 of human ACVR2B (Q13705, NP_001097). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Sheep, Hamster, Elephant, Panda, Dog, Bovine, Bat, Horse, Pig, Guinea pig (100%), Opossum, Turkey, Chicken, Xenopus, Drosophila (92%), Orangutan, Beetle (90%), Trout, Stickleback, Zebrafish (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (10 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for ACVR2B

Target: ACVR2B (Activin A Receptor, Type IIB (ACVR2B))

Alternative Name: ACTRIIB / ACVR2B

Background: Name/Gene ID: ACVR2B
Subfamily: Activin/TGFb
Family: Protein Kinase

Synonyms: ACVR2B, Activin A receptor type IIB, Activin receptor type-2B, ActR-IIB, ACTRIIB, Activin receptor type IIB, Activin A receptor, type IIB, HTX4

Gene ID: 93

NCBI Accession: NP_001097

Pathways: Hormone Transport, Cancer Immune Checkpoints