Vitronectin antibody (AA 381-478)

Catalog No. ABIN675518

The Rabbit Polyclonal anti-Vitronectin antibody has been validated for ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). It is suitable to detect Vitronectin in samples from Mouse and Rat. There is 1 publication available.

Quick Overview for Vitronectin antibody (AA 381-478) (ABIN675518)

Target: Vitronectin (VTN)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vitronectin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Vitronectin Antibody

Binding Specificity: AA 381-478

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Vitronectin

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Vitronectin antibody (ABIN675518)

Wang, Jiang, Peng, Guo, Shang, Chen, Wu, Chen: "Induced apoptosis of osteoblasts proliferating on polyhydroxyalkanoates." in: Biomaterials, Vol. 34, Issue 15, pp. 3737-46, (2013) (PubMed).

Target Details for Vitronectin

Target: Vitronectin (VTN)

Alternative Name: Vitronectin

Background:

Synonyms: VN, V75, VNT, Vitronectin, S-protein, Serum-spreading factor, VTN

Background: Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.

Gene ID: 7448

UniProt: P04004

Pathways: Autophagy, Smooth Muscle Cell Migration