PKC antibody (AA 371-388)

Catalog No. ABIN6757377

The Rabbit Polyclonal anti-PKC antibody has been validated for WB, ELISA and IP. It is suitable to detect PKC in samples from Human, Mouse, Rat, Cow, Chicken, Dog, Guinea Pig, Monkey, Pig, Rabbit and Sheep.

Quick Overview for PKC antibody (AA 371-388) (ABIN6757377)

Target: PKC (Protein Kinase C (PKC))

Reactivity: Human, Mouse, Rat, Cow, Chicken, Dog, Guinea Pig, Monkey, Pig, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-PKC Antibody

Binding Specificity: AA 371-388

Specificity: This immunoaffinity purified detects ~67-83kD proteins, corresponding to the apparent molecular masses of the different isoforms of PKC on SDS-PAGE immunoblots. This antibody is pan-specific and was designed to recognize all four cPKC isoforms (alpha, beta, gamma and delta). Species cross-reactivity: Human, mouse, rat, bovine, canine, chicken, guinea pig, monkey, porcine, rabbit and sheep.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Xenopus, Stickleback, Pufferfish, Zebrafish (94%).

Purification: Protein A Column

Immunogen: A 19 residue synthetic peptide KKDVVIQDDDVESTMVEK(C) based on the human PKC alpha (residues 371-388) with a cysteine (C) residue added and the peptide coupled to KLH. The cysteine residue at position 381 of the original sequence was substituted with a ser.

Isotype: IgG

Application Details

Application Notes: ELISA, IP (12.5 µg/mL), WB (2 µg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Borate buffer saline, pH 8.2, 40% glycerol.

Target Details for PKC

Target: PKC (Protein Kinase C (PKC))

Alternative Name: PKC / Protein Kinase C

Pathways: TCR Signaling, Regulation of G-Protein Coupled Receptor Protein Signaling, Interaction of EGFR with phospholipase C-gamma, Phototransduction