BNP antibody (AA 85-115)

Catalog No. ABIN678623

The Rabbit Polyclonal anti-BNP antibody has been validated for ELISA, IF (p) and IHC (p). It is suitable to detect BNP in samples from Rat. There are 2+ publications available.

Quick Overview for BNP antibody (AA 85-115) (ABIN678623)

Target: BNP (Brain Natriuretic Peptide (BNP))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BNP antibody is un-conjugated

Application: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BNP Antibody

Binding Specificity: AA 85-115

Cross-Reactivity: Rat

Predicted Reactivity: Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat BNP

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-BNP antibody (ABIN678623)

Rigazio, Hernández, Corral: "Cardiopathogenic mediators generated by GATA4 signaling upon co-activation with endothelin-1 and Trypanosoma cruzi infection." in: Microbial pathogenesis, Vol. 73, pp. 47-52, (2014) (PubMed).

Chavali, Tyagi, Mishra: "Differential expression of dicer, miRNAs, and inflammatory markers in diabetic Ins2+/- Akita hearts." in: Cell biochemistry and biophysics, Vol. 68, Issue 1, pp. 25-35, (2014) (PubMed).

Target Details for BNP

Target: BNP (Brain Natriuretic Peptide (BNP))

Alternative Name: BNP

Background:

Synonyms: BNP, Bnf, Natriuretic peptides B, Gamma-brain natriuretic peptide, Iso-ANP, Nppb

Background: Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity).

Gene ID: 25105

UniProt: P13205

Pathways: Hormone Activity