ESR2 antibody (AA 481-495)

Catalog No. ABIN1819778

The Mouse Monoclonal anti-ESR2 antibody has been validated for IHC and IHC (p). It is suitable to detect ESR2 in samples from Human.

Quick Overview for ESR2 antibody (AA 481-495) (ABIN1819778)

Target: ESR2 (Estrogen Receptor 2 (ESR2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ESR2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 57-3

Product Details anti-ESR2 Antibody

Binding Specificity: AA 481-495

Specificity: Recognizes the estrogen receptor beta 2 isoform. No cross-reactivity is seen with estrogen receptor beta 1 isoform. Estrogen receptor beta 2 is expressed in cell nuclei of a range of human tissues including the ovary, placenta, testis and vas deferens.

Purification: Purified

Immunogen: Synthetic peptide derived from the C terminus of the human estrogen receptor beta 2 isomer, C-GMKMETLLPEATMEQ. Percent identity by BLAST analysis: Human (100%), Marmoset (93%).

Type of Immunogen: Synthetic peptide

Isotype: IgG1

Application Details

Application Notes: Approved: IHC, IHC-P (1:50 - 1:500)

Not recommended for: WB

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for ESR2

Target: ESR2 (Estrogen Receptor 2 (ESR2))

Alternative Name: ESR2 / ER beta

Background: Name/Gene ID: ESR2
Subfamily: NR3 Steroid receptor
Family: NHR

Synonyms: ESR2, ESTRB, ER Beta, ERbeta, ER-BETA, ESR-BETA, ESRB, Estrogen receptor 2 (ER beta), NR3A2, Estrogen receptor beta, Estrogen receptor beta 4

Gene ID: 2100

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling