PITX3 antibody (AA 231-302) (HRP)

Catalog No. ABIN679997

The Rabbit Polyclonal anti-PITX3 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect PITX3 in samples from Mouse, Rat and Cow.

Quick Overview for PITX3 antibody (AA 231-302) (HRP) (ABIN679997)

Target: PITX3 (Pituitary Homeobox 3 (PITX3))

Reactivity: Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PITX3 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PITX3 Antibody (HRP)

Binding Specificity: AA 231-302

Cross-Reactivity: Cow, Mouse, Rat

Predicted Reactivity: Human,Dog,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PITX3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PITX3

Target: PITX3 (Pituitary Homeobox 3 (PITX3))

Alternative Name: PITX3

Background:

Synonyms: Homeobox protein PITX 3, Homeobox protein PITX3, MGC12766, Paired like homeodomain transcription factor 3, Paired-like homeodomain transcription factor 3, Pituitary homeobox 3, PITX 3, Pitx3, PITX3_HUMAN, PTX 3, PTX3.

Background: The transcription factor PITX3 is expressed selectively in the midbrain and regulates the differentiation and survival of dopaminergic neurons. Lack of this factor results in a degeneration similar to that seen in Parkinson's disease. PITX3 is also important in eye developement, mutations of the PITX3 gene have been associated with a familial form of cataracts.

Molecular Weight: 30-32kDa

Gene ID: 5309