PROX1 antibody (AA 151-250) (Cy5.5)
Quick Overview for PROX1 antibody (AA 151-250) (Cy5.5) (ABIN680508)
Target
See all PROX1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 151-250
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Cross-Reactivity
- Human, Mouse, Rat
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Predicted Reactivity
- Dog,Cow,Pig,Horse,Rabbit
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Prox-1
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Isotype
- IgG
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Application Notes
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FCM 1:20-100
IF(IHC-P) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- PROX1 (Prospero Homeobox 1 (PROX1))
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Alternative Name
- Prox1
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Background
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Synonyms: Prospero homeobox protein 1, Homeobox prospero-like protein PROX1, PROX-1, PROX1
Background: Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.
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Gene ID
- 5629
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UniProt
- Q92786
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Pathways
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
Target
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