Claudin 4 antibody (PE)

Catalog No. ABIN680753

The Rabbit Polyclonal anti-Claudin 4 antibody has been validated for WB. It is suitable to detect Claudin 4 in samples from Human, Mouse, Rat, Pig, Dog, Cow and Chicken.

Quick Overview for Claudin 4 antibody (PE) (ABIN680753)

Target: Claudin 4 (CLDN4)

Reactivity: Human, Mouse, Rat, Pig, Dog, Cow, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 4 antibody is conjugated to PE

Application: Western Blotting (WB)

Product Details anti-Claudin 4 Antibody (PE)

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLDN4

Isotype: IgG

Application Details

Application Notes: WB(1:100-500)
IHC-P(1:100-500)
IF(IHC-P)(1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Claudin 4

Target: Claudin 4 (CLDN4)

Alternative Name: Claudin 4

Background:

Synonyms: CPER, CPE-R, CPETR, CPETR1, WBSCR8, hCPE-R, Claudin-4, Clostridium perfringens enterotoxin receptor, CPE-receptor, Williams-Beuren syndrome chromosomal region 8 protein, CLDN4

Background: Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact made up of network of strands that act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition.

Molecular Weight: 22kDa

Gene ID: 1364

UniProt: O14493

Pathways: Hepatitis C