RGS5 antibody (AA 81-181) (Cy5)

Catalog No. ABIN680807

The Rabbit Polyclonal anti-RGS5 antibody has been validated for IF (cc) and IF (p). It is suitable to detect RGS5 in samples from Mouse and Rat.

Quick Overview for RGS5 antibody (AA 81-181) (Cy5) (ABIN680807)

Target: RGS5 (Regulator of G-Protein Signaling 5 (RGS5))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS5 antibody is conjugated to Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-RGS5 Antibody (Cy5)

Binding Specificity: AA 81-181

Specificity: This antibody may have a minor secondary cross-reactivity to the related proteins RGS3 and RGS4 based on a 67 % and 73 % non-sequential sequence similarity, respectively.

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse RGS5

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RGS5

Target: RGS5 (Regulator of G-Protein Signaling 5 (RGS5))

Alternative Name: RGS5

Background:

Synonyms: 1110070A02Rik, Regulator of G-protein signaling 5, RGS5

Background: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

Gene ID: 19737

UniProt: O08850

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling