DEFA4 antibody (AA 41-97)

Catalog No. ABIN680878

This Rabbit Polyclonal antibody specifically detects DEFA4 in ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for DEFA4 antibody (AA 41-97) (ABIN680878)

Target: DEFA4 (Defensin, alpha 4, Corticostatin (DEFA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEFA4 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-DEFA4 Antibody

Binding Specificity: AA 41-97

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Defensin alpha 4

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DEFA4

Target: DEFA4 (Defensin, alpha 4, Corticostatin (DEFA4))

Alternative Name: Defensin alpha 4

Background:

Synonyms: Neutrophil defensin 4, Defensin, alpha 4, HNP-4, HP-4, defensin, alpha 4, corticostatin, neutrophil defensin 4 precursor, neutrophil defensin 4 preproprotein.

Background: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils, it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq].

Gene ID: 1669