GAB2 antibody (PE-Cy5)
Quick Overview for GAB2 antibody (PE-Cy5) (ABIN681190)
Target
See all GAB2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Mouse, Rat
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Predicted Reactivity
- Dog,Cow,Pig,Horse,Rabbit
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Gab2
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Isotype
- IgG
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anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 273-484) antibody
GAB2 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (pTyr452) antibodyGAB2 Reactivity: Human, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (pSer159) antibodyGAB2 Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (Ser159) antibodyGAB2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 3-30), (N-Term) antibodyGAB2 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB21209 unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 357-607) antibodyGAB2 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 601-676) antibodyGAB2 Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (pSer623) antibodyGAB2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (pTyr643) antibodyGAB2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (C-Term) antibodyGAB2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
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Application Notes
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WB(1:100-500)
IHC-P(1:100-500)
IF(IHC-P)(1:100-500) -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
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Alternative Name
- Gab2
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Background
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Synonyms: GRB2-associated-binding protein 2, GRB2-associated binder 2, Growth factor receptor bound protein 2-associated protein 2, pp1, GAB2, KIAA571
Background: Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
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Molecular Weight
- 74kDa
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Gene ID
- 9846
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UniProt
- Q9UQC2
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Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, Warburg Effect
Target
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