RECK antibody (AA 801-900)

Catalog No. ABIN681418

This Rabbit Polyclonal antibody specifically detects RECK in WB, ELISA, IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for RECK antibody (AA 801-900) (ABIN681418)

Target: RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RECK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-RECK Antibody

Binding Specificity: AA 801-900

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RECK

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-RECK antibody (ABIN681418)

Liu, Chi, Lu, Zhang, Yamakawa: "Reversion-inducing-cysteine-rich Protein with Kazal Motif Is Involved in Intimal Hyperplasia in Carotid Arteries: A New Insight in the Prevention of Restenosis after Vascular Angioplasty." in: Annals of vascular surgery, Vol. 29, Issue 6, pp. 1293-9, (2015) (PubMed).

Siddesha, Valente, Sakamuri, Gardner, Delafontaine, Noda, Chandrasekar: "Acetylsalicylic acid inhibits IL-18-induced cardiac fibroblast migration through the induction of RECK." in: Journal of cellular physiology, Vol. 229, Issue 7, pp. 845-55, (2014) (PubMed).

Target Details for RECK

Target: RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))

Alternative Name: RECK

Background:

Synonyms: ST15, Reversion-inducing cysteine-rich protein with Kazal motifs, hRECK, Suppressor of tumorigenicity 15 protein, RECK

Background: Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.

Gene ID: 8434

UniProt: O95980