PDLIM3 antibody (AA 301-364) (HRP)

Catalog No. ABIN681832

This Rabbit Polyclonal antibody specifically detects PDLIM3 in ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for PDLIM3 antibody (AA 301-364) (HRP) (ABIN681832)

Target: PDLIM3 (PDZ and LIM Domain 3 (PDLIM3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDLIM3 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PDLIM3 Antibody (HRP)

Binding Specificity: AA 301-364

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDLIM3

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PDLIM3

Target: PDLIM3 (PDZ and LIM Domain 3 (PDLIM3))

Alternative Name: PDLIM3

Background:

Synonyms: Actinin associated LIM protein, Actinin-associated LIM protein, Alpha actinin 2 associated LIM protein, Alpha-actinin-2-associated LIM protein, DKFZp686L0362, Enigma homolog, PDLI3_HUMAN, PDLIM 3, PDLIM-3, PDLIM3, ALP, PDZ and LIM domain 3, PDZ and LIM domain protein 3.

Background: The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy.

Gene ID: 27295

UniProt: Q53GG5