AurB/C antibody (pThr198) (HRP)

Catalog No. ABIN683392

This Rabbit Polyclonal antibody specifically detects AurB/C in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for AurB/C antibody (pThr198) (HRP) (ABIN683392)

Target: AurB/C (AURKB/C) (Aurora Kinase B/C (AURKB/C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AurB/C antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA

Product Details anti-AurB/C Antibody (HRP)

Binding Specificity: pThr198

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Aurora B around the phosphorylation site of Thr232

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for AurB/C

Target: AurB/C (AURKB/C) (Aurora Kinase B/C (AURKB/C))

Alternative Name: Aurora B / Aurora C

Background:

Synonyms: Aurora B phospho T232, p-Aurora B phospho T232, AIK2, AIM1, ARK2, AurB, AURKB, Aurora 1, Aurora and Ipl1 like midbody associated protein 1, Aurora kinase B, Aurora related kinase 2, Aurora-B, Aurora/IPL1 related kinase 2, IPL1, Serine/theronine kinase 12, Serine/threonine protein kinase 12, STK1, STK12, STK5, AURKB_HUMAN.

Background: Aurora B is a mitotic protein kinase that phosphorylates histone H3 (probably on Serine 10), behaves as a chromosomal passenger protein, and may regulate several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis. It localizes to the inner centromere region from prophase to anaphase.

Gene ID: 9212