BCR antibody (pTyr177) (Cy5)
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- Target See all BCR Antibodies
- BCR (Breakpoint Cluster Region (BCR))
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Binding Specificity
- pTyr177
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BCR antibody is conjugated to Cy5
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human
- Predicted Reactivity
- Mouse,Rat,Pig,Rabbit,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human Bcr around the phosphorylation site of Tyr177 [PF(p-Y)VN]
- Isotype
- IgG
- Top Product
- Discover our top product BCR Primary Antibody
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anti-Breakpoint Cluster Region (BCR) (AA 139-280) antibody
BCR Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 1E11G12 unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 182-280) antibodyBCR Reactivity: Human WB, ELISA, IF, PLA Host: Mouse Monoclonal 2E5 unconjugated
anti-Breakpoint Cluster Region (BCR) (pTyr360) antibodyBCR Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (pTyr177) antibodyBCR Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 1-300) antibodyBCR Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (N-Term) antibodyBCR Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 1-1076) antibodyBCR Reactivity: Human WB, PLA Host: Rabbit Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 331-380), (pTyr360) antibodyBCR Reactivity: Human, Mouse WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (pTyr177) antibodyBCR Reactivity: Human WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (pTyr360) antibodyBCR Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- BCR (Breakpoint Cluster Region (BCR))
- Alternative Name
- Bcr (BCR Products)
- Background
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Synonyms: Bcr phospho Y177, BcrTyr177, ALL, BCR 1, BCR/ABL FUSION GENE INCLUDED, BCR/FGFR1 FUSION GENE INCLUDED, BCR/PDGFRA FUSION GENE INCLUDED, BCR1, breakpoint cluster region, CML, PHL, BCR_HUMAN.
Background: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.
- Gene ID
- 613
- Pathways
- Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
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