DOK2 antibody (pTyr299)

Catalog No. ABIN684163

This Rabbit Polyclonal antibody specifically detects DOK2 in WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro). It exhibits reactivity toward Human.

Quick Overview for DOK2 antibody (pTyr299) (ABIN684163)

Target: DOK2

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-DOK2 Antibody

Binding Specificity: pTyr299

Predicted Reactivity: Human,Dog,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human p56Dok2 around the phosphorylation site of Tyr299

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DOK2

Target: DOK2

Alternative Name: DOK2

Background:

Synonyms: Docking protein 2 56 kDa, Docking protein 2 antibody DOK 2, DOK R, Downstream of tyrosine kinase 2, p56dok 2, p56dok 2, p56DOK, p56dok2, DOK2, DOK2_HUMAN, Downstream of tyrosine kinase 2, OTTHUMP00000161710, OTTHUMP00000224923, p56dok 2, p56dok-2.

Background: The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]

Gene ID: 9046