DOK2 antibody (pTyr139) (HRP)

Catalog No. ABIN684187

This Rabbit Polyclonal antibody specifically detects DOK2 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for DOK2 antibody (pTyr139) (HRP) (ABIN684187)

Target: DOK2

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-DOK2 Antibody (HRP)

Binding Specificity: pTyr139

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human p56Dok2 around the phosphorylation site of Tyr139

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DOK2

Target: DOK2

Alternative Name: DOK2

Background:

Synonyms: DOK2 Tyr139, p-DOK2 Tyr139, Docking protein 2 56 kDa, Docking protein 2 antibody DOK 2, DOK R, Downstream of tyrosine kinase 2, p56dok 2, p56dok 2, p56DOK, p56dok2

Background: The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]

Gene ID: 9046