Ezrin antibody (pThr567) (Biotin)
Quick Overview for Ezrin antibody (pThr567) (Biotin) (ABIN684630)
Target
See all Ezrin (EZR) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pThr567
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Cross-Reactivity
- Mouse
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Predicted Reactivity
- Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from human Ezrin around the phosphorylation site of Thr567
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Isotype
- IgG
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Application Notes
- WB 1:300-5000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C for 12 months.
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Expiry Date
- 12 months
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- Ezrin (EZR)
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Alternative Name
- Ezrin
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Background
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Synonyms: Ezrin phospho T567, Ezrin phospho Thr567, p-Ezrin phospho T567, CVIL, CVL, cytovillin 2 , Cytovillin , DKFZp762H157, FLJ26216, MGC1584, p81, VIL 2 , VIL2, Villin 2, Villin2, EZRI_HUMAN.
Background: The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
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Gene ID
- 7430
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Pathways
- Maintenance of Protein Location
Target
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