FOXO1/FOXO4 (pSer197), (pSer256) antibody (Cy3)

Catalog No. ABIN684781

This Rabbit Polyclonal antibody specifically detects FOXO1/FOXO4 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FOXO1/FOXO4 (pSer197), (pSer256) antibody (Cy3) (ABIN684781)

Target: FOXO1/FOXO4

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Cy3

Application: Western Blotting (WB)

Product Details

Binding Specificity: pSer197, pSer256

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human FOXO4 around the phosphorylation site of Ser197

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: FOXO1/FOXO4

Background:

Synonyms: FOXO4 phospho S197, p-FOXO4 phospho S197, AFXSer197, Fork head domain transcription factor AFX1, AFX, AFX1, Afxh, ALL1-fused gene from X chromosome, Fork head domain transcription factor AFX1, Forkhead box O4, Forkhead box protein O4, FOXO 4, Mixed lineage leukemia, translocated to, 7, MLLT7, Myeloid lymphoid or mixed lineage leukemia translocated to 7, Myeloid/lymphoid or mixed lineage leukemia, translocated to, 7, Putative fork head domain transcription factor AFX1, FOXO1 Phospho-Ser256, Forkhead box protein O1 Phospho Ser256, FKHR Phospho-Ser256, FOXO1A Phospho-Ser256.

Background: These genes encode a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. Multiple transcript variants encoding different isoforms have been found for these genes. Both function as transcription factors involved in the regulation of the insulin signaling pathway.

Gene ID: 4303

UniProt: Q9WVH3