ITGAV/ITGB5 antibody (HRP)

Catalog No. ABIN685381

This Rabbit Polyclonal antibody specifically detects ITGAV/ITGB5 in ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for ITGAV/ITGB5 antibody (HRP) (ABIN685381)

Target: ITGAV/ITGB5 (Integrin alpha V, Integrin beta 5 (ITGAV/ITGB5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGAV/ITGB5 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ITGAV/ITGB5 Antibody (HRP)

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Integrin beta 5 and Integrin alpha V

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ITGAV/ITGB5

Target: ITGAV/ITGB5 (Integrin alpha V, Integrin beta 5 (ITGAV/ITGB5))

Alternative Name: Integrin Alpha V + Beta 5

Background:

Synonyms: CD51, MSK8, VNRA, VTNR, Integrin alpha-V, Vitronectin receptor subunit alpha, ITGAV

Background: The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Gene ID: 3685

UniProt: P06756