SSTR3 antibody (PE-Cy7)

Catalog No. ABIN685565

The Rabbit Polyclonal anti-SSTR3 antibody has been validated for WB. It is suitable to detect SSTR3 in samples from Human, Rat, Mouse, Cow and Dog.

Quick Overview for SSTR3 antibody (PE-Cy7) (ABIN685565)

Target: SSTR3 (Somatostatin Receptor 3 (SSTR3))

Reactivity: Human, Rat, Mouse, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSTR3 antibody is conjugated to PE-Cy7

Application: Western Blotting (WB)

Product Details anti-SSTR3 Antibody (PE-Cy7)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SSTR3

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SSTR3

Target: SSTR3 (Somatostatin Receptor 3 (SSTR3))

Alternative Name: SSTR3

Background:

Synonyms: somatostatin receptor 3, OTTHUMP00000028737, Smstr3, Somatostatin receptor 3, Somatostatin receptor subtype 3, Smstr 3, SS 3R, SS-3-R, SS3-R, SSR-28, SSR3_HUMAN, Sst3, SSTR 3, Somatostatin receptor type 3, SS3R, SSR28, Sst3, SSTR 3, SSTR3.

Background: Somatostatin is a tetradecapeptide that is widely distributed in the body. It acts on multiple organs in the body and also functions as a neuropeptide affecting electrical activity of neurons. Somatostatin acts to regulate numerous physiological processes by binding to and activating specific receptors in target tissues. There are five somatostatin receptor subtypes termed SSTR 1 to 5. They are G protein coupled receptors characterized by seven transmembrane helices with an extracellular amino terminal domain and an intracellular carboxy terminus. These receptors are activated by somatostatin secreted by nerve and endocrine cells and function in the regulation of numerous physiological processes such as the secretion of insulin, glucagon and growth hormone. The SSTRs also play a role in cell growth induced by neuronal excitation in both the central and peripheral nervous system. Somatostatin receptors have been implicated in numerous diseases ranging from Alzheimer's to cancers of the gastrointestinal tract, breast, prostate, and pituitary.

Molecular Weight: 46kDa

Gene ID: 6753