JunD antibody (AA 245-347) (Biotin)

Catalog No. ABIN685899

This anti-JunD antibody is a Rabbit Polyclonal antibody detecting JunD in WB, ELISA, IHC (p) and IHC (fro). Suitable for Rat.

Quick Overview for JunD antibody (AA 245-347) (Biotin) (ABIN685899)

Target: JunD (JUND) (Jun D Proto-Oncogene (JUND))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JunD antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-JunD Antibody (Biotin)

Binding Specificity: AA 245-347

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Jun D

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for JunD

Target: JunD (JUND) (Jun D Proto-Oncogene (JUND))

Alternative Name: Jun D

Background:

Synonyms: jun D proto-oncogene, JUND1, AP-1, JUND, JUND1, MGC6245, MGC72300.

Background: The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage, including non-AUG codons, results in the production of different isoforms.

Gene ID: 3727