GNRHR antibody (AA 201-328)

Catalog No. ABIN686917

This Rabbit Polyclonal antibody specifically detects GNRHR in WB, ELISA, IHC (p), IHC (fro), ICC, IF (p) and IF (cc). It exhibits reactivity toward Human and Rat and has been mentioned in 2+ publications.

Quick Overview for GNRHR antibody (AA 201-328) (ABIN686917)

Target: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNRHR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-GNRHR Antibody

Binding Specificity: AA 201-328

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GnRHR

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-GNRHR antibody (ABIN686917)

López-Doval, Salgado, Lafuente: "The expression of several reproductive hormone receptors can be modified by perfluorooctane sulfonate (PFOS) in adult male rats." in: Chemosphere, Vol. 155, pp. 488-97, (2016) (PubMed).

Liu, Li, Zhu, Yu, Guo, Zhou, Zheng, Qu, Huang, Chen, Wang, Ye: "Effects of di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-ovarian axis in adult female rats." in: Reproductive toxicology (Elmsford, N.Y.), Vol. 46, pp. 141-7, (2014) (PubMed).

Target Details for GNRHR

Target: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Alternative Name: GnRHR

Background:

Synonyms: HH7, GRHR, LRHR, LHRHR, GNRHR1, Gonadotropin-releasing hormone receptor, GnRH receptor, GnRH-R, GNRHR

Background: Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling.

Gene ID: 2798

UniProt: P30968