Fatty Acid Synthase antibody (AA 651-750)

Catalog No. ABIN687382

This Rabbit Polyclonal antibody specifically detects Fatty Acid Synthase in WB, ELISA, IHC (p), IF (p), IF (cc) and IHC (fro). It exhibits reactivity toward Human, Mouse, Rat and Goat and has been mentioned in 5+ publications.

Quick Overview for Fatty Acid Synthase antibody (AA 651-750) (ABIN687382)

Target: Fatty Acid Synthase (FASN)

Reactivity: Human, Mouse, Rat, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fatty Acid Synthase antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Fatty Acid Synthase Antibody

Binding Specificity: AA 651-750

Cross-Reactivity: Goat, Human, Mouse, Rat

Predicted Reactivity: Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse FASN

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Fatty Acid Synthase antibody (ABIN687382)

Yu, Zhao, Lai, Chu, Hao, Feng, Zhang, Liu, Cheng, Li, Shen, Min: "LncRNA as ceRNAs may be involved in lactation process." in: Oncotarget, Vol. 8, Issue 58, pp. 98014-98028, (2017) (PubMed).

Li, Ye, Wang, Li, Qiang, Yu, Tang, Liu: "Effect of Octreotide on Hepatic Steatosis in Diet-Induced Obesity in Rats." in: PLoS ONE, Vol. 11, Issue 3, pp. e0152085, (2016) (PubMed).

He, Guo, Qian, Zhang, Ren, Liu: "Synergistic hepatotoxicity by cadmium and chlorpyrifos: disordered hepatic lipid homeostasis." in: Molecular medicine reports, Vol. 12, Issue 1, pp. 303-8, (2015) (PubMed).

Chen, Luo, Ma, Wang, Cao, Xu, Zhu, Sun, Li, Yao, Kang, Gou: "MiR130b-Regulation of PPARγ Coactivator- 1α Suppresses Fat Metabolism in Goat Mammary Epithelial Cells." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142809, (2015) (PubMed).

Zhu, Luo, Wang, Yu, Wang, Shi, Sun, Lin, Li: "Inhibition of FASN reduces the synthesis of medium-chain fatty acids in goat mammary gland." in: Animal : an international journal of animal bioscience, Vol. 8, Issue 9, pp. 1469-78, (2014) (PubMed).

Target Details for Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Alternative Name: FASN/Fatty Acid Synthase

Background:

Synonyms: FAS, A630082H08Rik, Fatty acid synthase, Fasn

Background: Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.

Gene ID: 14104

UniProt: P19096

Pathways: AMPK Signaling