CXCL10 antibody (AA 35-98)

Catalog No. ABIN687442

This Rabbit Polyclonal antibody specifically detects CXCL10 in ELISA, FACS, IF (p), IF (cc), IHC (fro) and IHC (p). It exhibits reactivity toward Human, Mouse and Rat and has been mentioned in 5+ publications.

Quick Overview for CXCL10 antibody (AA 35-98) (ABIN687442)

Target: CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCL10 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CXCL10 Antibody

Binding Specificity: AA 35-98

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CXCL10

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CXCL10 antibody (ABIN687442)

Henschel, Cabrera, Kaldunski, Jia, Geoffrey, Roethle, Lam, Chen, Wang, Salzman, Hessner: "Modulation of the diet and gastrointestinal microbiota normalizes systemic inflammation and β-cell chemokine expression associated with autoimmune diabetes susceptibility." in: PLoS ONE, Vol. 13, Issue 1, pp. e0190351, (2018) (PubMed).

Lee, Cho, Cho, Bae, Kim, Park: "Establishment of a chronic obstructive pulmonary disease mouse model based on the elapsed time after LPS intranasal instillation." in: Laboratory animal research, Vol. 34, Issue 1, pp. 1-10, (2018) (PubMed).

Li, Nishikawa, Kaneda: "Platelet-cytokine Complex Suppresses Tumour Growth by Exploiting Intratumoural Thrombin-dependent Platelet Aggregation." in: Scientific reports, Vol. 6, pp. 25077, (2016) (PubMed).

Iversen, Reinert, Thomsen, Bagdonaite, Nandakumar, Cheshenko, Prabakaran, Vakhrushev, Krzyzowska, Kratholm, Ruiz-Perez, Petersen, Goriely, Bibby, Eriksson, Ruland, Thomsen, Herold, Wandall, Frische et al.: "An innate antiviral pathway acting before interferons at epithelial surfaces. ..." in: Nature immunology, Vol. 17, Issue 2, pp. 150-8, (2016) (PubMed).

Clancy-Thompson, Perekslis, Croteau, Alexander, Chabanet, Turk, Huang, Mullins: "Melanoma Induces, and Adenosine Suppresses, CXCR3-Cognate Chemokine Production and T-cell Infiltration of Lungs Bearing Metastatic-like Disease." in: Cancer immunology research, Vol. 3, Issue 8, pp. 956-67, (2015) (PubMed).

Target Details for CXCL10

Target: CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

Alternative Name: CXCL10

Background:

Synonyms: C7, IP10, CRG-2, INP1, IP-10, Ifi1, mob-1, Scyb1, gIP-1, C-X-C motif chemokine 1, 1 kDa interferon gamma-induced protein, Gamma-IP1, Interferon-gamma induced protein CRG-2, Small-inducible cytokine B1, Cxcl1, Crg2

Background: In addition to its role as a proinflammatory cytokine, may participate in T-cell effector function and perhaps T-cell development.

Gene ID: 15945

UniProt: P17515