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CD8 alpha antibody (CF®488A)

CD8A Reactivity: Human FACS, IF, T Host: Mouse Monoclonal C8-468 CF®488A

Catalog No. ABIN6935493

Datasheet as PDF

Target See all CD8 alpha (CD8A) Antibodies

CD8 alpha (CD8A) (CD8a Molecule (CD8A))
Reactivity
181

110

46

45

13

7

4

3

3

2

2

2

1

1

1

1

1

1
Human
Host
151

125

94
Mouse
Compatible Secondaries
Clonality
267

97

3
Monoclonal
Conjugate
133

41

29

25

24

8

8

8

7

6

5

5

5

5

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD8 alpha antibody is conjugated to CF®488A
Application
295

113

86

61

61

49

34

22

15

15

14

11

7

6

6

6

5

4

3

2

2

1

1

1

1
Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)

Purification

Purified by Protein A/G

Immunogen

Recombinant human CD8 protein

Clone

C8-468

Isotype

IgG1 kappa

Top Product

Discover our top product CD8A Primary Antibody
anti-CD8a Molecule (CD8A) (AA 22-235) antibody
CD8A Reactivity: Human FACS, WB, ELISA Host: Mouse Monoclonal 8H8A8 unconjugated

anti-CD8a Molecule (CD8A) antibody
CD8A Reactivity: Mouse FACS, IP, IHC (fro), IHC (p), ICC Host: Rat Monoclonal 53-6-7 unconjugated

anti-CD8a Molecule (CD8A) antibody
CD8A Reactivity: Mouse FACS, IP, IHC (fro), IHC (p), ICC, Func Host: Rat Monoclonal 53-6-7 unconjugated

anti-CD8a Molecule (CD8A) antibody (FITC)
CD8A Reactivity: Mouse FACS Host: Rat Monoclonal 53-6-7 FITC

anti-CD8a Molecule (CD8A) antibody (PE)
CD8A Reactivity: Mouse FACS Host: Rat Monoclonal 53-6-7 PE

anti-CD8a Molecule (CD8A) (AA 51-150) antibody
CD8A Reactivity: Human, Rat, Chicken FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) Host: Rabbit Polyclonal unconjugated

anti-CD8a Molecule (CD8A) antibody
CD8A Reactivity: Human IHC, WB, IP, ELISA Host: Rabbit Monoclonal 2F2 unconjugated Recombinant Antibody

anti-CD8a Molecule (CD8A) (AA 22-182) antibody
CD8A Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 6A9A5 unconjugated

anti-CD8a Molecule (CD8A) antibody
CD8A Reactivity: Human IHC, StM, ISt Host: Mouse Monoclonal C8-468 unconjugated

anti-CD8a Molecule (CD8A) (AA 28-196) antibody
CD8A Reactivity: Mouse, Rat FACS, IHC, WB, ELISA, ICC Host: Rabbit Polyclonal unconjugated

Application Notes

Positive Control: HuT78 or hPBL. Tonsil.
Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100),Optimal dilution for a specific application should be determined.

Restrictions

For Research Use only
Concentration

100 μg/mL

Buffer

10 mM PBS with 0.05 % BSA and 0.05 % azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C

Storage Comment

Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date

24 months
Target

CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Alternative Name

CD8A (CD8A Products)

Background

CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.

Molecular Weight

32kDa

Gene ID

925

UniProt

P01732

Pathways

TCR Signaling