CD8 alpha Products
(CD8a Molecule (CD8A))
Categories
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
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Featured CD8 alpha Categories
CD8 alpha Antibodies
High quality antibodies with extensive validation data.
CD8 alpha ELISA Kits
Reliable ELISA kits for a wide range of species.
CD8 alpha Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD8 alpha Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
FACS, WB, ELISA
Validations
- (5)
Cat. No.
ABIN7193490
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Mouse
Application
FACS, IP, IHC (fro), IHC (p), ICC, Func
Validations
- (8)
- (3)
Cat. No.
ABIN2749035
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Mouse
Application
FACS, IP, IHC (fro), IHC (p), ICC
Validations
- (8)
- (3)
Cat. No.
ABIN2749187
Quantity
0.1 mg
Datasheet
Datasheet
Recommended CD8 alpha ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965612
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965613
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971250
Quantity
96 tests
Datasheet
Datasheet
Recommended CD8 alpha Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274260
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274259
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7013444
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our CD8 alpha products
: "Outer membrane proteins of Salmonella typhimurium as an adjuvant in rabies vaccine." in: Clinical and experimental vaccine research, Vol. 10, Issue 2, pp. 132-140, (2021) (PubMed).: "Immune Response to Salmonella Enteritidis Infection in Broilers Immunized Orally With Chitosan-Based Salmonella Subunit Nanoparticle Vaccine." in: Frontiers in immunology, Vol. 11, pp. 935, (2020) (PubMed).
: "Implant delivering hydroxychloroquine attenuates vaginal T lymphocyte activation and inflammation." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 277, pp. 102-113, (2019) (PubMed).
: "CXCL14 suppresses human papillomavirus-associated head and neck cancer through antigen-specific CD8+ T-cell responses by upregulating MHC-I expression." in: Oncogene, (2019) (PubMed).
: "AAV vector-meditated expression of HLA-G reduces injury-induced corneal vascularization, immune cell infiltration, and fibrosis." in: Scientific reports, Vol. 7, Issue 1, pp. 17840, (2018) (PubMed).
: "CCDC88B is required for pathogenesis of inflammatory bowel disease." in: Nature communications, Vol. 8, Issue 1, pp. 932, (2018) (PubMed).
: "Effects of intranasal administration with Bacillus subtilis on immune cells in the nasal mucosa and tonsils of piglets." in: Experimental and therapeutic medicine, Vol. 15, Issue 6, pp. 5189-5198, (2018) (PubMed).
: "STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis. ..." in: Nature medicine, Vol. 24, Issue 7, pp. 1024-1035, (2018) (PubMed).
: "Infiltration and persistence of lymphocytes during late-stage cerebral ischemia in middle cerebral artery occlusion and photothrombotic stroke models." in: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 248, (2018) (PubMed).
: "Chemotherapy induces enrichment of CD47+/CD73+/PDL1+ immune evasive triple-negative breast cancer cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 6, pp. E1239-E1248, (2018) (PubMed).
Synonyms and alternative names related to CD8 alpha
CD8a molecule (Cd8a), uncharacterized LOC100125537 (LOC100125537), CD8 alpha (LOC100136450), CD8a molecule (CD8A), CD8 antigen, alpha chain (Cd8a), CD8a molecule (cd8a), T-cell surface glycoprotein CD8 alpha chain (LOC100126556), BB154331, cd8, CD8, Leu2, LOC100136450, Ly-2, Ly-35, Ly-B, Lyt-2, MAL, p32, RHACD8-4, zgc:136643Protein level used designations for CD8 alpha
- CD8 alpha
- CD8a molecule
- T-cell surface glycoprotein CD8 alpha chain
- CD8 antigen, alpha polypeptide
- T-cell surface glycoprotein CD8 alpha chain-like
- Lyt-2.1 lymphocyte differentiation antigen (AA at 100)
- T-cell surface glycoprotein Lyt-2
- CD8 antigen, alpha polypeptide (p32)
- Leu2 T-lymphocyte antigen
- OKT8 T-cell antigen
- T cell co-receptor
- T-cell antigen Leu2
- T-lymphocyte differentiation antigen T8/Leu-2
- T8 T-cell antigen
- CD8 antigen 32 kDa chain
- CD8 antigen alpha-chain
- CD8 antigen, alpha chain
- CD8 antigen, alpha-chain
- OX-8 membrane antigen
- CD8 antigen alpha polypeptide
- CD8 alpha chain
- T-cell surface molecule
- CD8 alpha molecule
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