ASRGL1 antibody

Catalog No. ABIN6936432

Product Details anti-ASRGL1 Antibody

Target: ASRGL1 (Asparaginase Like 1 (ASRGL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ASRGL1 antibody is un-conjugated

Application: Immunostaining (ISt), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificity: ASRGL1 (Asparaginase-like protein 1), also known as CRASH, is a 308 amino acid protein belonging to the Ntn-hydrolase family. Asparaginases utilize asparagine as a substrate to produce aspartic acid and ammonia. ASRGL1 has been identified as a autoantigenic protein that is present in the mid-piece of sperm after obstruction of the male reproductive tract. ASRGL1 is expressed highly in testis, but is also expressed in brain, kidney and gastrointestinal tissues. High levels of ASRGL1 have also been identified in ovarian, uterine and mammary tumors in comparison with normal tissues of the same origin.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant human ASRGL1 fragment

Clone: CRASH-1289

Isotype: IgG1 kappa

Application Details

Application Notes:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells. Fallopian Tube, Endometrium, Uterus or Cervix.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for ASRGL1

Target: ASRGL1 (Asparaginase Like 1 (ASRGL1))

Alternative Name: ASRGL1 (ASRGL1 Products)

Background: ALP1, ASGL1, Asparaginase like 1, ASRGL1, beta-aspartyl-peptidase, CRASH, isoaspartyl dipeptidase, isoaspartyl peptidase/L-asparaginase, L asparaginase, L asparagine amidohydrolase,ASRGL1 (Asparaginase Like 1)
Cellular localisation: Cytoplasmic and Nuclear

Molecular Weight: 17-25kDa

Gene ID: 80150, 535326

UniProt: Q7L266