CALB1 antibody (AA 7-96)
Quick Overview for CALB1 antibody (AA 7-96) (ABIN6936560)
Target
See all CALB1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 7-96
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Specificity
- The family of EF-hand type Ca2+-binding proteins includes Calbindin D28K, Calbindin D9K, S-100 (also designated oncomodulin). Calbindin D28K, also known as calbindin, CALB1, D-28K or vitamin D-dependent calcium-binding protein, is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, Calbindin D28K acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, Calbindin D28K modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, Calbindin D28K has been implicated to play a role in apoptosis and microtubule function.
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Cross-Reactivity (Details)
- Human.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- Recombinant fragment (around aa 7-96) of human CALB1 protein (exact sequence is proprietary)
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Isotype
- IgG1 kappa
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Application Notes
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Known_Application: ELISA (For coating, order antibody without BSA),Optimal dilution for a specific application should be determined.
Positive_Control: 293T or HepG2 cells. Prostate, Lung, Pancreas, Kidney and Liver.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Preservative
- Azide free
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Storage
- -20 °C,-80 °C
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Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Expiry Date
- 24 months
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- CALB1 (Calbindin (CALB1))
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Alternative Name
- CALB1
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Background
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Avian-type, CAB27, CALB 1, CALB, CALB1, CALB1_HUMAN, Calbindin 1 28 kDa, Calbindin, Calbindin D28, D 28K, D-28K, D28K, OTTHUMP00000166027, OTTHUMP00000225441, RTVL H protein, Vitamin D dependent calcium binding protein, Vitamin D dependent calcium binding protein avian type, Vitamin D-dependent calcium-binding protein,Calbindin 1 (CALB1)
Cellular localisation: Nuclear and Cytoplasmic -
Molecular Weight
- 52kDa
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Gene ID
- 793, 65425
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UniProt
- P05937
Target
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