CD38 antibody

Catalog No. ABIN6936680

This Mouse Monoclonal antibody specifically detects CD38 in FACS and IF. It exhibits reactivity toward Human.

Quick Overview for CD38 antibody (ABIN6936680)

Target: CD38

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD38 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: AT2

Product Details anti-CD38 Antibody

Specificity: This MAb reacts with a 45 kDa glycopeptide, which is a type II membrane glycoprotein with a transmembrane sequence near the NH2terminus. CD38 is a type II transmembrane glycoprotein that is present on early B- and T-cell lineages and activated B- and T-cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B-cells, mitogen-activated T-cells, monocytes and Ig-secreting plasma cells. CD38 is expressed on CD34+ cells. The CD34+CD38- population of hematopoietic stems cells defines the most pluripotent cells (e.g. blast colony forming cells).

Cross-Reactivity (Details): Human.

Immunogen: Human T cell line CCRF-CEM

Isotype: IgG3 kappa

Application Details

Application Notes:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence, Optimal dilution for a specific application should be determined.

Positive_Control: CCRF-CEM cells, Tonsil, Spleen or Skin.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Preservative: Azide free

Storage: 4 °C

Storage Comment: Store at 2 to 8°C. Antibody is stable for 24 months.

Expiry Date: 24 months

Target Details for CD38

Target: CD38

Background: Acute Lymphoblastic Leukemia Cells Antigen, ADP Ribosyl Cyclase 1, cADP-ribose Hydrolase 1, CD38H, NAD(+) Nucleosidase, NIM-R5 Antigen, p45, T10,CD38 (ADP Ribosyl Cyclase I)
Cellular localisation: Cell surface, cytoplasm and nucleus

Molecular Weight: ~45kDa (Glycoprotein), 35kDa (protein core)

Gene ID: 952, 479214

UniProt: P28907