CD48 antibody
Quick Overview for CD48 antibody (ABIN6936743)
Target
See all CD48 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
 - Reacts with human CD48, a 45 kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of marker for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.
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Cross-Reactivity (Details)
 - Human.
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Purification
 - 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
 - Human CD48 protein
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Isotype
 - IgG2a kappa
 
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Application Notes
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Known_Application: Functional Studies (Order Ab without Azide),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: Daudi, JY, Raji, Jurkat and human lymphocytes. Human lymph node and tonsil.
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Restrictions
 - For Research Use only
 
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Concentration
 - 1.0 mg/mL
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Buffer
 - Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Preservative
 - Azide free
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Storage
 - -20 °C,-80 °C
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Storage Comment
 - Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Expiry Date
 - 24 months
 
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- CD48
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Alternative Name
 - CD48
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Background
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                        B-cell activation marker, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, BLAST1, CD48 antigen (B cell membrane protein), Signaling lymphocytic activation molecule 2 (SLAMF2), SLAM family member 2,CD48 (Pan Leukocyte Marker)
Cellular localisation: Cell Surface - 
                                            
Molecular Weight
 - 45kDa
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Gene ID
 - 962, 243564
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UniProt
 - P09326
 
Target
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