FGA antibody

Catalog No. ABIN6937227

The Mouse Monoclonal anti-FGA antibody has been validated for ELISA, IF, FACS and Coat. It is suitable to detect FGA in samples from Human.

Quick Overview for FGA antibody (ABIN6937227)

Target: FGA (Fibrinogen alpha Chain (FGA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGA antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)

Clone: UC45

Product Details anti-FGA Antibody

Specificity: The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: . Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Human acute monoblastic leukemia cells.

Isotype: IgM kappa

Application Details

Application Notes:

Known_Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: Plasma.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Purified Ab WITHOUT BSA at 1.0mg/ml

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for FGA

Target: FGA (Fibrinogen alpha Chain (FGA))

Alternative Name: FGA

Background: Ac1873, Fba5e, FGA, Fib, Fib2, Fibrinogen alpha chain, Fibrinogen, A alpha polypeptide, Fibrinogen--alpha polypeptide chain, Fibrinopeptide A,Fibrinogen Alpha Chain
Cellular localisation: Secreted.

Molecular Weight: 30kDa

Gene ID: 2243, 351593

UniProt: P02671