FSHR antibody

Catalog No. ABIN6937270

The Mouse Monoclonal anti-FSHR antibody (Clone FSHR-1400) (ABIN6937270) specifically detects FSHR in IHC (f). The antibody is reactive with Human samples.

Quick Overview for FSHR antibody (ABIN6937270)

Target: FSHR (Follicle Stimulating Hormone Receptor (FSHR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FSHR antibody is un-conjugated

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: FSHR-1400

Product Details anti-FSHR Antibody

Specificity: Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant human FSHR protein

Isotype: IgG1 kappa

Application Details

Application Notes:

Known_Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Uterine Carcinoma.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for FSHR

Target: FSHR (Follicle Stimulating Hormone Receptor (FSHR))

Alternative Name: FSHR

Background: Follicle-stimulating hormone receptor, Follitropin receptor, FSH receptor, FSH-R, FSHRO, LGR1, ODG1, ovarian dysgenesis 1,FSH-Receptor (Ovarian Marker)
Cellular localisation: Cytoplasmic & Cell Surface

Molecular Weight: 75kDa

Gene ID: 2492, 1428

UniProt: P23945

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling