GATA3 antibody (AA 357-436)

Catalog No. ABIN6937305

The Mouse Monoclonal anti-GATA3 antibody has been validated for WB, ELISA, FACS and Coat. It is suitable to detect GATA3 in samples from Human.

Quick Overview for GATA3 antibody (AA 357-436) (ABIN6937305)

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GATA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Coating (Coat)

Clone: GATA3-2688

Product Details anti-GATA3 Antibody

Binding Specificity: AA 357-436

Specificity: GATA-3 is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types. GATA-3 expression is primarily seen in breast and urothelial carcinomas.'Therefore, GATA3 antibody can be useful in the identification of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment of human GATA3 protein (around aa 357-436) (exact sequence is proprietary)

Isotype: IgG

Application Details

Application Notes:

Known_Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: MCF-7 or T47D cells. Breast or Bladder Carcinoma.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for GATA3

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Alternative Name: GATA3

Background: GATA3, GATA binding protein-3, GATA-binding factor 3, GATA3, HDR, HDRS, Transacting T-cell-specific transcription factor GATA-3,GATA-3 (Breast and Urothelial Marker)
Cellular localisation: Nuclear

Molecular Weight: 50kDa

Gene ID: 2625, 524134

UniProt: P23771

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation