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ITGAL antibody

ITGAL Reactivity: Human FACS, IF, Func Host: Mouse Monoclonal CRIS-3 unconjugated

Catalog No. ABIN6937581

Datasheet as PDF

Target See all ITGAL Antibodies

ITGAL (Integrin alpha-L (ITGAL))
Reactivity
132

65

16

3

3

2

2

2

1

1

1

1
Human
Host
103

53

43

1
Mouse
Compatible Secondaries
Clonality
156

43

1
Monoclonal
Conjugate
72

27

23

18

7

6

6

4

4

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This ITGAL antibody is un-conjugated
Application
144

42

36

32

29

28

21

17

8

5

5

4

2

2

1

1

1

1

1
Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Specificity

Recognizes a protein of 180 kDa, identified as CD11a (Leucocyte Workshop II, Code N202). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses.

Cross-Reactivity (Details)

Human.

Purification

1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen

Stimulated human leukocytes

Clone

CRIS-3

Isotype

IgG2b kappa

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anti-Integrin alpha-L (ITGAL) antibody
ITGAL Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha-L (ITGAL) antibody
ITGAL Reactivity: Mouse FACS, IP, IHC (fro) Host: Rat Monoclonal M17-4 unconjugated

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ITGAL Reactivity: Human FACS, IP, Func Host: Mouse Monoclonal MEM-25 unconjugated

anti-Integrin alpha-L (ITGAL) antibody
ITGAL Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-25 unconjugated

anti-Integrin alpha-L (ITGAL) (AA 201-500) antibody
ITGAL Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha-L (ITGAL) antibody (Biotin)
ITGAL Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-25 Biotin

anti-Integrin alpha-L (ITGAL) antibody (PE)
ITGAL Reactivity: Human FACS Host: Mouse Monoclonal MEM-25 PE

Application Notes

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL) Functional Studies (Order Ab without BSA & Azide), Optimal dilution for a specific application should be determined.
Positive_Control: JY, HUT-78, MOLT-4, HL60, U937 and human leukocytes. Human lymph nodes and tonsils.

Restrictions

For Research Use only
Concentration

1.0 mg/mL

Buffer

Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative

Azide free

Storage

-20 °C,-80 °C

Storage Comment

Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date

24 months
Target

ITGAL (Integrin alpha-L (ITGAL))

Alternative Name

ITGAL (ITGAL Products)

Background

Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide, Integrin alpha-L, ITGAL, Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain, LFA 1 alpha (LFA1A), Ly15, Ly21, p180,CD11a / Integrin L / LFA-1 Chain
Cellular localisation: Cell Surface

Molecular Weight

180kDa

Gene ID

3683, 174103

UniProt

P20701

Pathways

Activated T Cell Proliferation, Integrin Complex