MAGEA4 antibody

Catalog No. ABIN6937797

The Mouse Monoclonal anti-MAGEA4 antibody has been validated for IHC (f). It is suitable to detect MAGEA4 in samples from Human.

Quick Overview for MAGEA4 antibody (ABIN6937797)

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAGEA4 antibody is un-conjugated

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: CPTC-MAGEA4-1

Product Details anti-MAGEA4 Antibody

Specificity: The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types, but not in normal tissues, with the exception of testis and placenta.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human MAGEA4 protein

Isotype: IgG2c kappa

Application Details

Application Notes:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: HepG2 cell lysate, melanoma, testes and placenta.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for MAGEA4

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Alternative Name: MAGEA4

Background: CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B, cancer/testis antigen 1.4, Melanoma-associated antigen 4,Melanoma Antigen Family A, 4 / MAGEA4
Cellular localisation: Cytoplasmic and nuclear.

Molecular Weight: 45-50kDa

Gene ID: 4103, 37107

UniProt: P43358