MAGEA4 antibody

Catalog No. ABIN6940003

Product Details anti-MAGEA4 Antibody

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAGEA4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Purification: Purified by Protein A/G

Immunogen: Recombinant full-length human MAGEA4 protein

Clone: CPTC-MAGEA4-1

Isotype: IgG2c kappa

Application Details

Application Notes:

Positive Control: HepG2 cell lysate, melanoma, testes and placenta.

Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for MAGEA4

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Alternative Name: MAGEA4 (MAGEA4 Products)

Synonyms: Mage-a4 antibody, MAGEA4 antibody, CT1.4 antibody, MAGE-41 antibody, MAGE-X2 antibody, MAGE4 antibody, MAGE4A antibody, MAGE4B antibody, melanoma antigen, family A, 4 antibody, MAGE family member A4 antibody, Magea4 antibody, MAGEA4 antibody

Background: The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types, but not in normal tissues, with the exception of testis and placenta.

Molecular Weight: 45-50kDa

Gene ID: 4103

UniProt: P43358