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ODC1 antibody

ODC1 Reactivity: Human WB, IF, FACS, IHC (f) Host: Mouse Monoclonal ODC1-486 unconjugated
Catalog No. ABIN6938104
  • Target See all ODC1 Antibodies
    ODC1 (Ornithine Decarboxylase 1 (ODC1))
    Reactivity
    • 88
    • 50
    • 31
    • 15
    • 15
    • 1
    Human
    Host
    • 55
    • 35
    • 2
    Mouse
    Clonality
    • 52
    • 40
    Monoclonal
    Conjugate
    • 41
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ODC1 antibody is un-conjugated
    Application
    • 74
    • 29
    • 24
    • 21
    • 19
    • 19
    • 14
    • 13
    • 13
    • 9
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificity
    Recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
    Cross-Reactivity (Details)
    Human. Mouse. Rat.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant human ODC-1 protein
    Clone
    ODC1-486
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product ODC1 Primary Antibody
  • Application Notes

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: PC3 cells. Placenta, Prostate or Testicular carcinoma.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    ODC1 (Ornithine Decarboxylase 1 (ODC1))
    Alternative Name
    ODC1 (ODC1 Products)
    Background
    Ornithine decarboxylase structural 1, RNODC,Ornithine Decarboxylase-1 (ODC-1)
    Cellular localisation: Cytoplasmic
    Molecular Weight
    53kDa
    Gene ID
    4953, 467701
    UniProt
    P11926
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