PAX5 antibody

Catalog No. ABIN6938117

This Mouse Monoclonal antibody specifically detects PAX5 in WB, ELISA and Coat. It exhibits reactivity toward Human.

Quick Overview for PAX5 antibody (ABIN6938117)

Target: PAX5 (Paired Box 5 (PAX5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAX5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Coating (Coat)

Clone: PAX5-2060

Product Details anti-PAX5 Antibody

Specificity: The PAX5 gene is a member of thepaired box (PAX)family of transcription factors. The central feature of this gene family is a novel, highly conservedDNA-binding domain, known as thepaired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute toneoplastic transformation. The PAX5 gene encodes theB-celllineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development andspermatogenesis.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human PAX5 protein

Isotype: IgG1 kappa

Application Details

Application Notes:

Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Positive_Control: Daudi or Ramos cells. Tonsil, spleen, Lymph Node or Colon Carcinoma.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for PAX5

Target: PAX5 (Paired Box 5 (PAX5))

Alternative Name: PAX5

Background: B cell lineage specific activator, BSAP, EBB-1, KLP, Paired box 5,PAX5 / BSAP (Early B-Cell Marker)
Cellular localisation: Nuclear

Molecular Weight: 42kDa

Gene ID: 5079, 654464

UniProt: Q02548