RBP1 antibody

Catalog No. ABIN6938316

The Mouse Monoclonal anti-RBP1 antibody is suitable to detect RBP1 in samples from Human. It has been validated for IHC (f).

Quick Overview for RBP1 antibody (ABIN6938316)

Target: RBP1 (Retinol Binding Protein 1, Cellular (RBP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RBP1 antibody is un-conjugated

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: RBP-872

Product Details anti-RBP1 Antibody

Specificity: Recognizes a protein of 21 kDa-25 kDa, identified as retinol binding protein-1 (RBP1). This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post-transnationally and results in defective delivery and supply to the epidermal cells.

Cross-Reactivity (Details): Human. Monkey. Goat. Rabbit. Rat. Mouse.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant human retinol binding protein-1 (RBP1)

Isotype: IgG1 kappa

Application Details

Application Notes:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Hepatic or ovarian carcinoma.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for RBP1

Target: RBP1 (Retinol Binding Protein 1, Cellular (RBP1))

Alternative Name: RBP1

Background: Cellular retinol-binding protein I, CRBP1, CRBP2, RBP1, RBP2, RBP4, RBPC, Retinol binding protein 1, Retinol binding protein 1 cellular, Retinol binding protein 2 cellular, Retinol binding protein 4 plasma,Retinol Binding Protein-1 (RBP1)
Cellular localisation: Cytoplasmic

Molecular Weight: 21-25kDa

Gene ID: 5947, 5948, 5950

UniProt: P02753, P09455, P50120