SAT1 antibody
Quick Overview for SAT1 antibody (ABIN6938356)
Target
See all SAT1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Spermidine/spermine N1-acetyltransferase 1 (SAT1 or SSAT1) is the key regulatory enzyme in the catabolism of polyamines, catalyzing acetylation of spermidine or spermine to generate N1-acetyl spermidine or N1-acetyl spermine, and N1, N12-diacetylspermine. The cellular level of SAT1 is normally extremely low, but it is induced rapidly by a variety of stimuli, including polyamines, polyamine analogs, toxic chemicals, certain drugs, and growth factors. Downregulation of SAT1 has been reported in Epstein-Barr virus positive Burkitt's lymphoma cells.
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Cross-Reactivity (Details)
- Human.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- Recombinant full-length human SAT1 protein
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Isotype
- IgG2a kappa
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Application Notes
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Known_Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.
Positive_Control: Human liver tissue lysate, human tonsil or kidney.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Preservative
- Azide free
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Storage
- -20 °C,-80 °C
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Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Expiry Date
- 24 months
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- SAT1 (Spermidine/spermine N1-Acetyltransferase 1 (SAT1))
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Alternative Name
- SAT1
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Background
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DC21, Diamine acetyltransferase 1, Diamine N acetyltransferase 1, EC 2.3.1.57, KDSD, KSDX, Polyamine N acetyltransferase 1, Putrescine acetyltransferase, SAT1, spermidine/spermine N1 acetyltransferase alpha, SSAT, SSAT1,Spermidine or Spermine N1-Acetyltransferase 1
Cellular localisation: Cytoplasm. -
Molecular Weight
- 20kDa
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Gene ID
- 6303, 28491
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UniProt
- P21673
Target
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